Sleepus Sleep Support Capsules for Menopause

Why menopause messes with your sleep

You're dragging all day, then 3 am hits and your brain decides it's time to replay every conversation you've had since 1998. Sound familiar? Stress and a racing mind at night are the #1 reasons women tell us they wake up between 2 and 4 am.

And when sleep goes sideways, everything feels harder: focus, mood, patience, energy.

That's why we made Sleepus.

It brings together clinically studied Lactium®, L-theanine, magnesium and slow-release melatonin to help support a calm mood, relaxation and more restful sleep.*

Made for the broken-up sleep so many of us get in perimenopause and menopause.

Questions about our formula? Check out our FAQs below.

Magnesium: 75 mg (12% DV) (as Albion® buffered Magnesium Bisglycinate Chelate)

Lactium® (100% milk protein hydrolysate): 175 mg

Suntheanine® L-Theanine: 50 mg

Melatonin (as MicroActive® Melatonin): 1.5 mg

Other Ingredients: Hypromellose, Microcrystalline Cellulose, Vegetable Stearate, Silica

Contains: Milk

Important Notes

Lactium & Dairy: Lactium is made from milk protein (a casein hydrolysate), so Sleepus contains milk. It has only a trace of lactose, roughly 1 mg per capsule. If you have a milk allergy, dairy sensitivity or lactose intolerance, consult your healthcare provider before use.

Warning: For adults only. Take at bedtime. Do not drive or operate machinery for 5 hours after taking melatonin. Avoid alcohol or other products that cause drowsiness.

Consult your healthcare provider if you are pregnant, nursing, taking medication, have a medical condition, or are experiencing long-term sleep difficulties. Not recommended for children without medical guidance.

Keep out of reach of children.

Albion® is a registered trademark of Balchem Corporation. Lactium® is a registered trademark of Ingredia. Suntheanine® is a registered trademark of Taiyo International, Inc. MicroActive® is a registered trademark of BioActives, LLC.

The research behind these ingredients

Sleepus is built around Lactium, a clinically studied milk peptide (alpha-casozepine). Each capsule provides 175 mg of Lactium and 50 mg of L-theanine, matching or above the amounts in the 2022 trial below.

• Messaoudi et al., British Journal of Nutrition, 2005: adults under lab-induced stress had lower blood pressure and a lower cortisol response versus placebo.
• Kim et al., European Journal of Clinical Nutrition, 2007: 63 women, 150 mg/day for 30 days, improved emotional, intellectual and digestive stress symptoms.
• de Saint-Hilaire et al., The Open Sleep Journal, 2009: 32 adults, 150 mg/day for 28 days, greater improvement in sleep quality (PSQI) versus placebo.
• Thiagarajah, Chee and Sit, Nutrients, 2022: 39 adults with poor sleep, 150 mg peptide plus 50 mg L-theanine for 4 weeks, about 45 minutes more total sleep than placebo (p<0.001). Salivary cortisol fell 34.6% in one stage of the trial, but not significantly across the whole trial.
• Bulman et al., Sleep Medicine Reviews, 2025: a review of 19 L-theanine studies found better self-reported sleep quality and next-day functioning, but no change in measured sleep time.

Want the full breakdown of the research? Read our article Why Do I Wake Up at 3 AM During Menopause?.

Note: these are small human trials, and some were supported by the ingredient maker. One 2024 trial of Lactium and L-theanine in mostly midlife women didn't find a difference from placebo on sleep questionnaires (Lim et al., Frontiers in Nutrition, 2024). We'd rather you hear that from us. These studies support structure and function statements, not disease-treatment claims.

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

How to Take Sleepus

Take 1 to 2 capsules 30 to 60 minutes before bed.

Take Sleepus every night; it's made for consistent, daily use, not just once in a while. It takes time. In the published studies on Lactium, people took it daily for about 4 weeks, and in one study the changes were bigger at 4 weeks than at 2 weeks. So give it at least 4 weeks of nightly use before you decide if it's working for you.

Each capsule provides 175 mg of Lactium. The published studies used 150 mg a day.

Tips from Our Founder

Andrea has been taking Sleepus for over three years and has found that consistency makes all the difference. Stick with the label directions of 1 to 2 capsules, and listen to your body.

Taking Morphus Magnesium too? Sleepus already has 75 mg of magnesium per capsule, so check both labels and stay under 350 mg a day from supplements (NIH).

I've already tried melatonin and magnesium. Why would this be different?

Fair question. A lot of women tell us the same thing. Sleepus isn't melatonin with extras. It's built around Lactium, a calming peptide from milk that you won't find in a plain melatonin or magnesium supplement, with L-theanine, a gentle dose of magnesium and 1.5 mg of slow-release melatonin. We can't promise it will work where other things didn't. What we can tell you is what's in it, how much, and what the studies found, which is all on this page. Give it 4 weeks of nightly use before you decide.

Why do I wake up in the middle of the night even if I take melatonin?

Falling asleep and staying asleep are controlled by different nighttime signals.

Melatonin helps signal that it's time to sleep, but waking in the night is often tied to stress and a racing mind, which so many of us notice more in midlife.

That's why Sleepus pairs a low dose of slow-release melatonin with Lactium and L-theanine.

Is there solid research on the ingredients in Sleepus?

We use branded ingredients with published human research, and we'll tell you what the studies found, including their limits:

Lactium® (alpha-s1 casein hydrolysate):

A peptide from milk protein. In a 2022 trial, 150 mg of it plus 50 mg of L-theanine every night for 4 weeks was linked to about 45 minutes more total sleep than placebo (Thiagarajah, Chee and Sit, Nutrients, 2022). One capsule of Sleepus has 175 mg of Lactium and 50 mg of L-theanine. In lab research, alpha-casozepine, the peptide in Lactium, interacts with GABA-A receptors, which are involved in relaxation. It has not been shown to be habit-forming.*

L-Theanine (Suntheanine®):

An amino acid found in tea. A 2025 review of 19 studies found L-theanine may support how well people feel they slept and how they feel the next day, though it didn't change measured sleep time (Bulman et al., Sleep Medicine Reviews, 2025). It has not been shown to be habit-forming.*

Albion® Magnesium Bisglycinate Chelate:

A well-absorbed, gentle form of magnesium, bound to the amino acid glycine.

MicroActive® Melatonin:

Micronized melatonin (tiny particles) with a sustained-release design that, according to its maker, releases it gradually over about 6 hours instead of all at once. Our bodies make less melatonin as we get older. Check out this study/review: https://pubmed.ncbi.nlm.nih.gov/33969545/

Does Sleepus contain dairy?

Yes. Lactium® is made from milk protein (it's a casein hydrolysate), so Sleepus contains milk. According to its maker, Lactium has only a trace of lactose, about 0.6%, which works out to roughly 1 mg per capsule. If you have a milk allergy, a dairy sensitivity or lactose intolerance, please check with your healthcare provider before taking Sleepus.

I wake up between 2 and 4 am every morning and have trouble falling back asleep. Will Sleepus help me?

Both L-theanine and Lactium® have been studied for supporting sleep and a healthy stress response. In our survey of 2,156 women, 67% said a racing mind is what keeps them up at night. We can't promise results for any one person, so give it 4 weeks of nightly use and see how your nights feel.

I wake up once or several times a night to pee. Will Sleepus help reduce the number of bathroom visits during the wee hours of the night (pun intended)?

We get this question a lot, and we want to be straight with you. Sleepus isn't made to cut down on bathroom trips, and we haven't found research showing its ingredients do that. Getting up to pee at night can have a lot of different causes, so it's worth bringing up with your healthcare provider. What Sleepus is designed for is helping you feel calm and relaxed at bedtime, which may make it easier to drift back off after you get up.

How long does it take for Sleepus to start working?

Every body responds differently, and this one takes time. In the published studies on Lactium, people took it every day for about 4 weeks, and in one of them the changes were bigger at 4 weeks than at 2 weeks. So give Sleepus at least 4 weeks of consistent, nightly use before you decide whether it's working for you. NOTE: Each capsule contains 1.5 mg of melatonin. The label directions are 1 to 2 capsules (1.5 to 3 mg of melatonin). Please don't take more than 2 capsules unless your healthcare provider has told you to.

What if it doesn't work for me?

Give it a fair run first: every night, for at least 4 weeks. If it's still not right for you, that's what our 100-Night Promise is for. Email us within 100 nights and we'll refund your first bottle.

Why did you add magnesium to the Sleepus formula?

Magnesium is involved in over 300 processes in the body, including muscle and nerve function. And about half of us don't get enough magnesium from food alone, according to the NIH Office of Dietary Supplements. According to our own customer research, stress is the top reason women tell us they're having trouble sleeping in perimenopause and menopause, and magnesium plays a part in the body's normal stress response: see this review. We're sharing this as background on magnesium's general role in the body. It isn't a claim about what Sleepus does. We recommend trying Sleepus on its own first.

Why did you include melatonin in the Sleepus formula?

Melatonin is a hormone your body makes to signal that it's time to sleep. It's a big part of your circadian rhythm, your body's sleep/wake cycle. As you get older, a lot of things can throw your melatonin and your circadian rhythm off, like dropping estrogen and progesterone, changes in serotonin, and not getting enough daylight. Every capsule of Sleepus has 1.5 mg of sustained-release melatonin, formulated to support your natural sleep cycle.*

Is it safe for women in perimenopause and menopause to take melatonin?

Melatonin is generally well tolerated for short-term use, and Sleepus keeps the dose low at 1.5 mg per capsule. The research in menopausal women specifically is mixed: a 2026 review of seven trials didn't find a clear sleep benefit from melatonin alone (Du and Tan, Frontiers in Nutrition, 2026), which is one reason Sleepus isn't built on melatonin by itself. Melatonin can interact with some medications, so check with your healthcare provider or pharmacist if you take any.

Melatonin makes me groggy, will that happen with your melatonin too?

Everyone responds differently to different brands and doses, so listen to your body. Many women start with one capsule. Sleepus contains 1.5 mg of melatonin per capsule, and the label directions are 1 to 2 capsules.

How long will your MicroActive® melatonin release during the night?

According to its maker, it releases gradually over about 6 hours.

Is Sleepus addictive?

None of the ingredients in this formula have been shown to promote addiction.

Can I take Sleepus with sleeping pills?

Since we are not medical professionals, we recommend speaking to your doctor when it comes to sleeping medication.

Can I take Sleepus with Morphus Magnesium?

Lots of women take both, but check the numbers first. Sleepus has 75 mg of magnesium in each capsule, so 2 capsules is 150 mg. Morphus Magnesium adds more. The NIH upper limit for magnesium from supplements is 350 mg a day for adults, so read both labels and stay under it. The ingredients have been studied on their own, not tested together as a pair. If you take any medications, check with your healthcare provider first.

Can I take Sleepus with food?

Yes. The label doesn't ask you to take Sleepus on an empty stomach. Take 1 to 2 capsules 30 to 60 minutes before bed, with or without a light snack, whichever sits better with you.

Where is Sleepus manufactured?

It is manufactured in the US.

Can men take Sleepus or The 3AM Bundle?

Yes, they can.

Do you have any sleep tips for me?

Yes, we do. Here are 15 Tips to Sleep Better in Menopause.